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Pfizer – Vaccine of Corona Virus distribution

The best, effective, and safe solution for the COVID-19 is now successful. The American Pharmaceutical company Pfizer has found the vaccine for the COVID-19 Pandemic. So now the situation will be under control.

An American multinational pharmaceutical corporation Pfizer Inc. is the world’s largest pharmaceutical company. It ranks 57 in the year 2018 in the list of US corporations by total revenue for Fortune 500. The headquarters of the company is located in New York City.

The company produces the medicines and vaccines of immunology, oncology, cardiology, endocrinology, and neurology. The products for the company are blockbuster drug Lipitor and others. The Chairman and CEO of the company are Albert Bourla. It employs 88,300 employees.

Pfizer partner with BioNTech in 2020 for the research and development of COVID-19 mRNA vaccine candidates. So on July 27, 2020, they made an announcement to begin a global phase 2/3 safety and efficacy clinical study to evaluate mRNA vaccine candidate BNT162b2.

On June 2, 2020, company make an announcement to the breakthrough Growth initiative program invest in publicly tradeable drug developer to fund treatment candidate and give access to its scientific expertise.

In November 2020, the company announce COVID-19 vaccine test on 43,500 people found 90% effective, and it was considered a “milestone”

Efforts made by the company:

For the Vaccine, the discussion was done with the FDA and after that company currently drop 32 case interim analyses and made the first interim analysis at less than 62 cases.

And the conclusion of that was evaluable case count reach 94 and DMC perform its first analysis on all cases. The case turns between vaccinate individuals and those who receive placebo indicate vaccine efficacy rate more than 90% in a week after the second dose.

Then it was concluded that protection is 28 days after initiation of vaccination. It consists 2-dose schedule. The final vaccine efficacy percentage may be different.

DMC has no report for any safety concerns and recommends that the study continue to collect additional safety and efficacy data as plan. Data will be discussed with regulatory authorities all over the World.

Pfizer 3

Britain Approve Pfizer’s COVID-19 vaccine on Wednesday jumping ahead of the United States and Europe to become the West’s first country having the vaccine for the COVID-19.

WHO (World Health Organization) lead the development of FAF which goals for successful COVID-19 vaccine and treatment are distribute on an equal basis all over the countries.

So it is a key part of Access to COVID-19 Tools (ACT) Accelerator a global collaboration to accelerate development, production, and equitable access to COVID-19 test, treatment, and vaccines.

Framework advice once a COVID-19 vaccine is shown to be safe and effective and authorized for using it. So every country should get the vaccine in the proportion of the deaths and newly recorded cases in the world.

With the blunder and regulation, the U.S. Food and Drug Administration ensures the quality of the vaccine, the safety of the vaccine, and effectiveness of the vaccine.

2020 COVID-19 vaccine by Pfizer:

Pfizer started its testing. Four variants of COVID-19 Vaccine for concluding the COVID-19 pandemic. So that it lengthen human trials to thousands of patients by September 2020.

The company injects doses of potential vaccine BNT162b2, but it was under development by the German biotechnology company Biotech. It is based in Mainz, Germany into first human participants in the U.S. in May.

Pfizer announces about the vaccine that they will deliver millions of doses in the month of October. So it expects to prepare hundreds of millions of doses in 2021.

BioNTech and Pfizer announce that partners four mRNA vaccine candidates had won fast track designation from the U.S. Food and Drug Administration (FDA).

Company launch into phase 3 testing in the last week of July 2020 on 30,000 people and slate to pay $1.95 billion for 100 million doses of vaccine by the U.S. Government.

It Cost $39 for two doses and the company said that it would not lower rates for other countries till the outbreak is no longer a pandemic. The CEO of the company announced in the private sector produce vaccine should make a profit.

In September 2020, Pfizer and BioNTech announce they completed talks with the European Commission to provide an initial 200 million vaccine dose to the EU with the option to supply another 100 million dose at later date.

Pfizer announces on November 9, 2020, that they have apply for Emergency use authorization from FDA for vaccines. So on December 2, 2020, the UK approves Pfizer’s vaccine, becoming the first country to approve a COVID-19 vaccine. It is helpful in facilitating the timely development of COVID-19 Vaccines.


The hurdle for the Vaccine:

The vaccine for COVID-19 was effective in the test and it requires the refrigeration of 70-80 degrees. So this is the biggest hurdle in the distribution of vaccines as most of the country can refrigerate around -2 to -8 degrees. In this temperature, the vaccine gets spoil after 5 days.

It was reported that Pfizer will start testing the COVID-19 vaccine develop by BioNTech on a broader range of subjects including children of the age 12. So it was the first coronavirus vaccine trial to include children in the U.S.

Distribution of Corona Vaccine:

In Bengaluru the discussion regarding the distribution of the Corona vaccine has been conclude to the vaccine will be distributed on the basis of the cases. Because regular immunization is proven to be the best and people have recovered with it.

But many of them have not adopted it. So the government is planning for indicating the vaccine to only 100 persons per day of the hospitals and the person having a serious condition. And the people admit in community halls and the makeshift tent will be vaccine at a later stage.

For AEFI the identification of vaccine meets requirements of Covid inoculation and they are based on SOP issues by health ministry. The vaccination area must have a waiting room, and the waiting room must have the facility for sanitization/hand washing area, the social distancing of 6 feet for seating, appropriate behavior.

In the vaccination rooms, 1 recipient with the patient, 2 of the vaccines are having 4 condition ice packs, the hands should be sanitize and the mask is compulsory, and Anaphylaxis Kit.

Similarly, in the observation room, space should be there and the vaccinated person has to wait for 30 minutes. And there should be the maintenance of physical distancing.

Every site should have 5 vaccination officers, it includes a watchman, 3 rooms, waiting, vaccination, and observation. In an hour 13-14 people will be given vaccination.

In the United Kingdom as per the health ministry, the vaccine will be distribute to the public. As per the National Expert Group on Vaccine Administration. It will be on the basis of the Prioritization of Population groups.

The first to receive the coronavirus vaccine in India:

There is a recommendation to provide vaccine first to the workers and health care providers, and the frontline workers. After that, the vaccination to 50 years above and less than 50 years’ people should be prioritized for the vaccine. The adult person who gets infectious with the coronavirus has to wait for their turn to be vaccination.



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